Increased risk of hepatotoxicity and temporary drug withdrawal during treatment of active tuberculosis in pregnant women.

Increased risk of hepatotoxicity and temporary drug withdrawal during treatment of active tuberculosis in pregnant women.

Publication date: Jun 24, 2020

Few studies have focused on treatment of tuberculosis (TB) during pregnancy. The aim of this study was to evaluate the risk of adverse events, particularly liver toxicity in pregnant women during treatment for active TB.

We conducted a retrospective study on pregnant and age-matched non-pregnant women receiving treatment for active TB at four hospitals Western Sweden between 1992 and 2017.

A total of 135 women were included, 40 pregnant and 95 non-pregnant. The frequency of severe hepatotoxicity was 40% in pregnant women and 6% among non-pregnant women (p?

Concepts Keywords
Drug Withdrawal TB
Frequency Medical specialties
Hepatotoxicity RTT
Liver Toxicity Medicine
Pregnancy Drugs
Sweden Hepatotoxins
Tuberculosis Hepatology
Hepatotoxicity
Toxicology
Niacin
Tuberculosis management

Semantics

Type Source Name
disease MESH tuberculosis
pathway KEGG Tuberculosis

Original Article

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